Best advice so far, BC30cal !

I too lean to the Velocitor, mostly for the slight edge over the Mini-Mags for penetration.

About half the 'yotes will run on me. Usually about the distance you would expect for Rimfire stuff,, + or -, 70 yards or so. I usually go for the double lung shot on 'yotes because I know they will be dead 'shortly'.

I expect similar results on problem deer, up to about the 80# maximum live weight. Velocitor (and Mini-Mags) there also, with Velocitors again 1st choice. Over the 80# weight 'shortly' often gets different to predict.

The protocol on head and neck shots here is, as quickly as possible approach and another to the heart lung/area AND brain pan. Seen a few of those head and neck shots that were 'dead' get up and take off again.

Don't know the OP's situation, safety seems to be his paramount problem.

Out of this thread.