I have been loading them and killing critters with them for years. They work and have been accurate in all of my rifles. I have not shot the .270, but have used them in .308, 7 mag, 6mm Remington and .243. I have killed over 100 white-tailed deer with the 100-grain Interlock in my 6 mm. Very few bullets were recovered.
I now load Partitions for elk, but for deer and antelope, Interlocks have always been what I use.