Bloodworks,
I have taken elk with a 264 Win Mag,270 Win, 7mm Rem Mag, 7mm WSM, 308 Win and an 8mm Rem Mag. With Hornady interlocks, interbonds, GMX, Nosler partions, Accubonds, Swift A/frame, Scrocco, Corelocks and plain old factory load that I do not even know what bullet was loaded in.
The short answer is put the bullet in the right place and you will need to worry about how much freezer wrap you have.
8mmwapiti