I mount them which ever way it needs to be for proper eye relief. Mounting a VX3 4.5-14 on a M70 long action a month or so ago required me to reverse the front base in order to get the scope far enough back for proper eye relief.
I've had some alignment issues with talley lightweights and I'm about to quit using them. On one M70 I had a pretty bad misalignment that went away when I swapped to leupold dual dovetails. You never know whether it's the rings/bases themselves or the receiver that's crooked, but in this case I think the talleys weren't straight. I suspect that's the case with this M70 also, after I got it mounted the windage was pretty far off, I had enough internal adjustment to zero it but didn't like it. I'm going to switch mount and see if that fixes it. I lapped the talleys and bedded the scope using JB weld so I've got a very stress free setup, but I don't like how much windage adjustment it took. Here's a picture taken after lapping but before bedding which shows why I always like to lap talley's. You can see the high points where the anodizing was removed which illustrates just how out of alignment they were before lapping. It's easy to see why folks get ring marks from unlapped rings that are this crooked.
Here it is after bedding:
It's stress free now but when bore sighting it took a LOT of right windage to get it on paper, much more than I like even though I was able to get it zeroed. I don't know if the problem is in the talley's or the scope mounting holes but I tend to blame the talleys since I didn't have that problem before on this rifle. I'm going to switch mounts/rings and see if it goes away.