Well since all I use is cast slugs I'll have to say.........use a cast slug, there's no bad angle's with cast, just make sure you are lined up on the vitals on the other end. I like 2 holes, one in & one out & I've had that for 45 years of using cast on big game, I've never recovered a bullet, ever! I used a Ruger 480 & a 370 gr cast slug on my moose, he went about 15 yds, I've taken many elk, bears, deer, antelope, mountain lion & african game, I don't understand all the running, I've never, not once had an animal run 100 yds when shot with a cast slug. I did have one run a long ways once when I used a 270 gr Speer Gold Dot on a cow elk but it wasn't the bullets fault it was mine, another elk bumped into her just as I made the shot & it hit her to far back, she ran maybe half a mile, laid down 3-4 times & I finished it. A bullet thats 1/2" in diameter at 1000-1200 fps thats put in the right place is unbeatable. I took 11 animals last year with revolvers, hogs, 3 deer, a bear & an elk, all with cast, none ran 10 yds, most didn't run at all!
Use that 44 with confidence on that moose.
Bear, 6' 9", Ruger 44 magnum 250 gr Keith
cow elk, Ruger 45, 260 gr Keith
Record book warthog, FA 475, 370 gr. LBT
Forkhorn muley, Ruger 357 maxi, 173 gr Keith
Mountain Lion, S&W 357, 173 gr Keith
I take it back, one animal did run 40 yds, this Wyoming buck, shot him with my Bisley 41 magnum & 230 gr cast, thats the entry hole, he was facing me. Also took 2 whitetails in Montana with the 41 & 230 gr Keith, then there were 6 hogs in Texas, all with a 41 blackhawk & 230 gr cast, you get the idea, most died in their tracks.
Dick
Dick