The best patterns in my .45 shotshells were always when using a shortened .410 shot cup with a thin over-shot card wad. You give up some shot capacity with the .410 shot cup but make up for it with a better pattern that's denser in the center to longer distances, and more consistent shot to shot. Direct contact of the shot against the rifling makes for poor patterns most of the time.
I use the old RCBS 45 ACP shotshell dies to crimp my over shot wad; these work well for any 45 caliber straight wall case.
These are for the .460 S&W, but same idea. The target was shot at 10 yards (most pistol shotshell patterns you'll find are at much closer distances).