I gave up on Barnes making a .375 cal.TTSX at around 290 to 300 grains for longer range use. I've had great accuracy using the 270 TSX in my 375 AI, but the BC's equal those of a brick!!! So,I finally went down in bullet weight for the better BC. It took some time for everything to come together,days off,hot days and no wind.I got to do a little load work last week,and was pretty impressed if it wasn't a fluke. All groups were pretty good,the best 3 shot group was just under 0.6"at a 3058 average velocity.If I can duplicate that group(or real close) a few more times,I may have something for this hunting season.We drew antelope tags,and with the season only about 6 weeks away,I might get the opportunity to test it on game. memtb

Project complete! The more I use RL 17, the more I like it! 40 rounds, in 3 shot groups, with the largest velocity spread at 15 fps. Most were under 10 fps, and most groups ran between 3/4" and an inch. I settled on a 3133 fps average(highest velocity group was around 3170fps), with the group under 1/2". No heavy bolt lift, and primers were "just" starting to flatten, with all shooting done in mid 80's to mid 90's (allowing rifle and ammo to reach ambient) for temp's. Contacted Leupold for the turrets. Now for the opportunity to put it to use. memtb

I'm having good results in my .375 Ruger with them as well.

BCSteve, any load data? I've got a couple boxes of them for a .375 Ruger (20" Howa), but data is pretty thin on the ground. Nonexistent, actually. I've googled my azz off, have several of the major manuals, contacted Barnes directly, and all I've got is direction to start somewhere between a 235 and 270 gr TSX.

83.0 gr. of H414 and the Barnes 250 gr. TTSX gives me 2880 fps from my 23" barreled Ruger Hawkeye African, and sub-MOA accuracy.

83.5gr of H4350 gives me 2700fps in my 20" Ruger Alaskan.

BobinNH has been running 250 gr Bitteroots for quite some time in a 375 H&H. I don't recall the data he sent me but I have been trying it with 250 GR TSX's also. I believe the powder was H4350. I need to look at my notes and get back. Might be a good starting point for you fellas.

I'm shooting cloverleafs in my H&H with the 270 TSX and 73 grains of R15. But I'm only getting 2600 fps. I'd like 2800 fps, as this is my back up elk rifle. I've got a box of the 250 TTSX, I just haven't put them together because the first load shoots so damn well.

I try and tell myself that it won't matter if the 270 TSX doesn't open at 350 yards, because its 270 grains. Trying to make a 50 yard DGR a 400 yard elk rifle is folly, but it shoots so well I hate to put it up for sale. A 2800+ load with the TTSX that shoots as well as the load I currently have would solve a lot of my problems, and keep me from looking at a 7 Rem mag in a Cooper or LAW.

Lee,
I shoot both the 270 gr. TSX and the 250 gr. TTSX out of my .375 Ruger. MV of the 270 gr. load is 2800 fps, and 2880 fps for the TTSX. I could push the TTSX faster, but it is very accurate- maybe a tad better than the TSX.
I wouldn't hesitate to try those 250 grainers. You shouldn't have any problems getting them to 2800 fps out of your .375, and may find out as I did that they are every bit as accurate. Plus, a better BC to boot.
I use Ramshot Big Game powder for the 270 gr. load, and H414 for the 250 gr. load.

I have to retract that about h4350, I believe it was re15

First off, do you think the 375 is "enough gun" for an antelope??

Marginally so,but I'll risk it! I've used it several times in the past, and it's worked so far! I'll let you know in a few weeks. memtb

That seems quite slow? With a max book load of Big Game/270 TSX I'm getting 2700+ out of a 20" Ruger Alaskan. A guy should be able to get 2800+ with the 250?

With a 20" 375 Ruger, I've found I can get at least 100 fps greater with RL 17 over RL 15 at what is my best guess of comparable pressures. But with RL 17, my 270 and 300 bonded grainers were more accurate than the 250 ttsx.

Have you tried Accubonds? Good BC's and I have heard they work well with wide range of impact velocity. I'll try them when I use up the bullets I have.

I actually need to re-chrono that load. On two different days I was getting a constant 100fps difference with the same load, 2700 fps on day and 2800 fps on the other day over several rounds. Maybe the clouds or my set up, not sure.

Tag. This is the exact same project I was working on last year before we had our second child in July and all my time went... elsewhere.

The last I recall was buying a really long drop tube to get every last grain of RL15 into those cases before compressing the ever-loving he11 out of the powder. These bullets seemed to shoot better the faster I pushed them in my M70 Safari Express.

-John