Shoot these at 3,000-3,200 fps and I think you are asking for trouble. That would be o.k. for varmints.
That is essentially what I was told when I started shooting the 125gr Hornady spire points in one of my M98s in 8x57. I've not chrono'd the load, but would guess they're poppin' along at least 2800fps or a bit more, from the muzzle. I liked them because they were far more accurate than any of the 150gr bullets previously loaded for deer in that particular rifle.
First buck killed was at about 85 yards. Bullet entered behind the left shoulder and exited the offside shoulder after breaking it. Dead deer on the ground where it had stood, end of story.
Since then I've killed several other deer with it, including one large baldy at slightly over 100yds, that crushed the spine, killing her instantly, (downhill shot in brush at a deer that was facing me. Was aiming at the base of her neck, she turned to depart, just as I pulled the trigger).
Probably never use any other bullet in that rifle.