I've settled on the 286gr Nosler at 2400 from my 20.5" barrel. So far it's done fine on various deer, goats, and one big brown bear. I get 2525 with the 250gr Accubond but the 286s shoot fast enough for my trajectory needs and I firmly believe the 286 partition will penetrate more than any 250 grain bullet. That's not so say I don't think the 250 would work okay on a bear at spitting distance, I'm just happy to trade longer range for the better close range bear option.
