I agree with Mule Deer the 30-06 and a 12 gauge would do it all, but how boring would that be? I have bought, used and sold several hundred rifles, shotguns and handguns over the years and learned something from each one. Someone asked me once why I needed another gun and I asked what need had to do with anything. I am building my ultimate, for now, deer rifle, a Remington 721 action in 257 Roberts. I have a safe full of rifles that will kill deer, but the 257 seems ideal for a 68 year old who is starting to feel the years a bit. Next year I am sure something else might turn my head.