I'm using my bolt action 6.8 SPC with 110 grain projectiles at just over 2800 fps more and more these days, and it ain't let me down yet. I'm also putting together a .257 to shoot 110's at 3000-3100 fps at the moment. As you get older the lighter rifles are more appealing, so you really need to go down in power otherwise the recoil might start to be an issue. Reducing muzzle blast as you get older is another benefit of the milder cartridges.