Don't know about 22lr but I've seen 2 deer shot by a 22WMR and know specifically of another. First 2 were shot by mistake. Friend of mine thought they were squirrels.
Damn, you must have some big ass squirrels in your area !
Well,......that's what he said anyway. But that was long ago and far away.
Colossians 3:17 (New King James Version) "And whatever you do in word or deed, do all in the name of the Lord Jesus, giving thanks to God the Father through Him."