The Semprio is chambered in 375 ruger.
I have never been in africa and will probably never go there hunting but found this out of curiosity:
http://www.rifleshootermag.com/2011/01/04/ammunition_375ruger_061207/Looks like they are doing ok.
Hopefully one of the big american companies like Remington Ruger i.e. will make their own version of the "inline repeater" for like 500USD. That would make it easier to enjoy the consept for a lot more hunters.
Paal
