A friend of mine has a 1-8 Tikka 22-250. He killed a very nice whitetail buck in the fall with a 70 grain Accubond from it, and has used that combo on several hogs too. He's an experienced hunter. He says they dig deep and he likes them a lot.
I have the same rifle and shot a few rounds of his Accubond handloads (over Reloader 15) with it. The few I shot showed potential for accuracy though I'd want to play with the seating depth some.
I'm that friend, though he may not claim me.
In addition to the buck it took a couple of does, and like Ted said several hogs of various sizes. I like them, have yet to recover one, and they don't seem to have the "Accubomb" trait that I've seen in another caliber. Have purposely shot a few hogs with it in the shoulder and still had complete penetration. Accuracy is very good in my rifle over RL-15, running about 3300 fps.
Bill
