No, not in the heart, that would be a rush.
I bet.
I have a high tolerance to the "caines", like novacaine at the dentist. Years ago I was having some work done on a front tooth. He did me up as good as he normally would, took the crown off the front tooth he was working on and started in to using the drill or something. I jumped a bit. He said "you can still feel that?". Yep I said.
So he gets out the needle and sticks it directly into the root of that tooth. Immediate rush, runs up alongside my nose, past the bridge of my nose between my eyes, over the top of my skull, and hits me at the base of the skull/top of my spine. I think my eyes did something because he said " Looks like you felt that one".
I said 'You can do that again!!!"