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Originally Posted by gunner500
Hurt my back once, Doc gave me a 10 day bender, it is from the devil and will cause a man to wind up on death row if not careful, i hate that shlt!

This

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Originally Posted by Nestucca
Originally Posted by gunner500
Hurt my back once, Doc gave me a 10 day bender, it is from the devil and will cause a man to wind up on death row if not careful, i hate that shlt!

This

+2. It gave me anger issues I didn't know I had.

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What a surprise. A drug works for some and some have the bad side effects out weight the benefits.

Maybe they should put warnings on a label?....

Nothing new here. I’m deathly allergic to ancef, most of you get/have gotten doses after surgery .


Decades of voting for the lesser of two evils has gotten us just that.....
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Are bone density problems an issue???

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Doc rx's me Pred for gout when nothing else will touch it. 40 mg burst dose, then down titrate from there usually taking 6 days. Did the same for a severe swollen poison oak/ivy reaction. Works well in those applications. And yes, I get 'roid rage from it. Wife and kids give me wide berth when I'm on a Pred bender.

Mom was on it 7 years for PMR trying to keep SED rates down. It worked in that regard, but destroyed her bones. As we speak, she's bedridden. T3 is gone - like not there. T2 and T4 are swollen with compression fractures, and T5 is extremely hot - ortho's words, not mine. Ortho showed me the MRI.
The bone is so brittle and weak that there's nothing to screw into - like punky wood. Can't do the injectable cement either because there's nothing there to attach it to. Ortho said it's the years of taking Pred and an otherwise healthy lady is probably going to die from it.


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My wife gets on it periodically, give her dreams, rage, it’s awful, but it works!


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Originally Posted by CharlieFoxtrot
Doc rx's me Pred for gout when nothing else will touch it. 40 mg burst dose, then down titrate from there usually taking 6 days. Did the same for a severe swollen poison oak/ivy reaction. Works well in those applications. And yes, I get 'roid rage from it. Wife and kids give me wide berth when I'm on a Pred bender.

Mom was on it 7 years for PMR trying to keep SED rates down. It worked in that regard, but destroyed her bones. As we speak, she's bedridden. T3 is gone - like not there. T2 and T4 are swollen with compression fractures, and T5 is extremely hot - ortho's words, not mine. Ortho showed me the MRI.
The bone is so brittle and weak that there's nothing to screw into - like punky wood. Can't do the injectable cement either because there's nothing there to attach it to. Ortho said it's the years of taking Pred and an otherwise healthy lady is probably going to die from it.

Really sorry to hear that...
I've done the treatment three times, once for gout and twice for bronchitis. The second time with bronchitis my MD wouldn't give me any antibiotics, she won't for a viral infection. A few days after the week of prednisone the bronchitis came back with a vengeance. I skipped my MD, went to RediMed. That doctor uped the doseage and extended the treatment to two weeks, also gave me a Zpac. That knocked the crp out of the bronchitis. My MD never said a word about me doing an end around.

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Miracle drug for my gout. Can't take NSAIDS.

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Originally Posted by Leenie3freezers
Hi JG, I was diagnosed with pulmonary sarcoidosis a bunch of years ago. Unfortunately the doctors missed diagnosing it until I'd lost 42% of lung capacity, Started at 40 mg, as you have, but after the two year regime, it came back and had to do it all again. Good news is that was the end of it. Seven years on prednisone, But I've been in remission over 20 years, Sounds like you're tolerating the prednisone really well, I hope it kills those little granulomas and never comes back. Eileen Clarke


Thank you very much Eileen. I have hope my situation will turn out like yours.


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I have taken Prednisone many times for chronic hives that nothing else would work..I had an open prescription but I found a combo that worked as well and quit taking Prednisone..Prednisone is often prescribed for MS..Nasty stuff to some,it never bothered me much....


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Get off that schitt. Take anti-inflammatory like curcumin and cod liver oil.


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Originally Posted by AJ300MAG
Originally Posted by CharlieFoxtrot
Doc rx's me Pred for gout when nothing else will touch it. 40 mg burst dose, then down titrate from there usually taking 6 days. Did the same for a severe swollen poison oak/ivy reaction. Works well in those applications. And yes, I get 'roid rage from it. Wife and kids give me wide berth when I'm on a Pred bender.

Mom was on it 7 years for PMR trying to keep SED rates down. It worked in that regard, but destroyed her bones. As we speak, she's bedridden. T3 is gone - like not there. T2 and T4 are swollen with compression fractures, and T5 is extremely hot - ortho's words, not mine. Ortho showed me the MRI.
The bone is so brittle and weak that there's nothing to screw into - like punky wood. Can't do the injectable cement either because there's nothing there to attach it to. Ortho said it's the years of taking Pred and an otherwise healthy lady is probably going to die from it.

Really sorry to hear that...
I've done the treatment three times, once for gout and twice for bronchitis. The second time with bronchitis my MD wouldn't give me any antibiotics, she won't for a viral infection. A few days after the week of prednisone the bronchitis came back with a vengeance. I skipped my MD, went to RediMed. That doctor uped the doseage and extended the treatment to two weeks, also gave me a Zpac. That knocked the cr@p out of the bronchitis. My MD never said a word about me doing an end around.


I wouldn't call it an end around so much as advocating for your own health. With Pred you usually see results quickly. Viral infections and bacterial infections are 2 different animals. Doc shoulda done a culture and figure out which one you had. That Z-pac is an anti-biotic and that's what knocked that infection down. Good on ya for making the call to see someone else - more people should.


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Pred has probably saved my life a couple of times, but as I said earlier, it can really open up the gates of hell. I would be the last one to tell someonenot to take it, but watch out for yourself and for others. One of the best things that ever happened in my life was the relief I felt when a doctor told me: " It's the Prednizone that's doing it." Once I knew it was a drug reaction, all the weird stuff became much easier to handle.

The liver transplant guy gave me a lot of good advice. According to him, Pred puts you on a roller coaster. Your adrenal glands are pretty well shut down. The Pred tells them there's an excess of adrenaline in your system, so it shuts down adrenaline production. You're now dependent on the "fix" of fake adrenaline every so many hours. When you're up, you're on top of the world. However, when you come down. . .

"Your body takes the sincere lack of adrenaline and a sign that you're dying," George said. "We go our whole lives, basically feeling well, because we have adrenaline in our systems. When that disappears, it mimics the body shutting down in preparation for death."

There are some things that are locked up in your head on the level of Jungian archetypes that trigger. I had dreams of death, decay, really morbid stuff. It can be real Fright-Night stuff.

Bottom line: If you know someone on cortical steroids, be a buddy and let them know this stuff can really send them for a loop. Often times knowing it's just the drug that's doing it can be a huge help. Since my run-in in 91, I've probably helped half a dozen people by broaching the subject.


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shaman, advise is spot on. Pred is akin to what I would think that Meth would be like if I had ever taken it. I never got any REM sleep the whole time I was on the Pred...I hope I never have to take it again. I talked to the Dr about it, and there are stronger and weaker versions of the Pred.

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Jittery as fug this morning! 2 more days, thank goodness. Joint pain is down, thats a plus. Geez tho this stuff messes with ya! Gonna go for a walk here in a bit and see if that helps. Feel like I gotta keep movin.

Glad it helps a bunch of you folks, really am. But seems to fug me up. Wish the doc woulda give me a little more heads up.

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Prednisone, Prednisolone and analogs are synthetic replacements for the natural cortisol or hydrocortisone already in your body and released by the Circadian rhythm in your body during the sleep cycle particularly about 2 am.

The strength of the various analogs are due to differences in the metabolic route, hence duration, not strength as such.

The dreams and nightmares are caused by disturbances in the subconscious re-arranging of the Archetypical Jungian symbols, which becomes your reality on awakening.

Adrenaline (epinephrine) is not the main player , duration of action is far too short, Aldosterone, and ADH, are trying to regulate your Na, and blood pressure. (Renal fatigue) which are also made by the adrenal gland.

The glandular secretions are pulsatile or wavelike in the frequency of release. The secretions are trying to co-ordinate to the secretions of thyroid t4 (which comes too little and too late, ) and testosterone (why the Succubus visits you every morning)

Tumerin an Cod liver oil are excellent ideas and anti-inflammatories.

Also getting on a short course of hydrocortisone for renal fatigue.


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Originally Posted by CharlieFoxtrot
Originally Posted by AJ300MAG
Originally Posted by CharlieFoxtrot
Doc rx's me Pred for gout when nothing else will touch it. 40 mg burst dose, then down titrate from there usually taking 6 days. Did the same for a severe swollen poison oak/ivy reaction. Works well in those applications. And yes, I get 'roid rage from it. Wife and kids give me wide berth when I'm on a Pred bender.

Mom was on it 7 years for PMR trying to keep SED rates down. It worked in that regard, but destroyed her bones. As we speak, she's bedridden. T3 is gone - like not there. T2 and T4 are swollen with compression fractures, and T5 is extremely hot - ortho's words, not mine. Ortho showed me the MRI.
The bone is so brittle and weak that there's nothing to screw into - like punky wood. Can't do the injectable cement either because there's nothing there to attach it to. Ortho said it's the years of taking Pred and an otherwise healthy lady is probably going to die from it.

Really sorry to hear that...
I've done the treatment three times, once for gout and twice for bronchitis. The second time with bronchitis my MD wouldn't give me any antibiotics, she won't for a viral infection. A few days after the week of prednisone the bronchitis came back with a vengeance. I skipped my MD, went to RediMed. That doctor uped the doseage and extended the treatment to two weeks, also gave me a Zpac. That knocked the cr@p out of the bronchitis. My MD never said a word about me doing an end around.


I wouldn't call it an end around so much as advocating for your own health. With Pred you usually see results quickly. Viral infections and bacterial infections are 2 different animals. Doc shoulda done a culture and figure out which one you had. That Z-pac is an anti-biotic and that's what knocked that infection down. Good on ya for making the call to see someone else - more people should.


Before i started the D3, Z Sulphate, K2 and one Hydroxychloroquine a week i normally got severe viral bronchitis about every fall and spring.
Used to have to getbon ABs to knock it.
Then a lung specialist had me start 50 mg Pred in AM every OTHER day when i started getting it.
Normally i only had to take 3 doses over 6 days before i was well and never had to get on the ABs for several years by doing that.

By skipping every other day it doesnt knock your own adrenal gland cortisol production out and no need to taper off Pred if only used for a short time.

Your comments on this would be appreciated Charley and Etoh.


Last edited by jaguartx; 03/13/21.

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Important to understand that D3 is a hormone, not a vitamin (vitamin= vital amine, , D3 is cholesterol derivative with no amine groups. )

also that adrenaline is not a hormone, only called that because most is made in the adrenal. It does contain an amine group, and by convention fits into the vitamin group .

most of the nomenclature is so outdated its hardly usable.

allosteric , the attachment of a protein, enzyme or group to a receptor site to activate------

most important aspect of biochemistry. not only are the time constants different for the same person in different places of the body,, for the same reaction, there are thousands of different ones.

and as the state of the physiological envoirnment is in a different allosteric state in each person . When compared to mathematical physiological modeling, rocket science is kids play.

the plural of anecdote is not data.


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one of the most important systems to get back on line, that covers a broad category of issues is the melatonin -Circadian system.

Melatonin is not a sleeping aid, it is a HORMONE-- call it the happy hormone.

it is part of the tryptophan , serotonin -- neural communication system of your body.



first thing in any evaluation is a complete medical history.


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Originally Posted by Etoh
one of the most important systems to get back on line, that covers a broad category of issues is the melatonin -Circadian system.

Melatonin is not a sleeping aid, it is a HORMONE-- call it the happy hormone.

it is part of the tryptophan , serotonin -- neural communication system of your body.



first thing in any evaluation is a complete medical history.


What can one do to get it back online and up and running well

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