I have the DR200S, I'm lighter than you but the bike would by far haul your azz around.
I'm off pavement about 80% of the time but make short, 15 to 20 mile highway runs to get to some locations. I can run it up to 65 mph pretty quick and eventually hit 80.
That's where I'd think you'd be happier with the DR400, maybe I would too. I missed a chance at buying a good Honda 250, it could be the ticket for you as well.
I'd just hate to go with a heavier bike now that I have this one.
The 200 I can manipulate really well off the road, my aging light weight body still has enough umph to make a light bike do what I want it to in hard spots. I've bounced my way up some really steep rocky climbs and been surprised with the control I can maintain.
With the DR200 weighing in at 275 pounds, it's a bike I ride, it don't ride me. Then there's the loading it on the rack on the back of the RV part. I would not want a heavier bike when it comes to that maneuver.
The DR400 is 320 pounds, so you'd probably find it to be similar in maneuverability and manipulating, you have a 100 pounds of body weight on me and a few inches of height.
The bike is super quite, when I first purchased it I was recommended to put a performance exhaust system on it to enhance performance and make it sound like a real motorcycle.
Really glad I didn't do that. I can sneak around pretty stealthy like in the mountains without spooking every critter I come across.
I put it in neutral and shut it off for downhill runs and then it's just tire noise, some places for miles at a time.
Last fall I put 1700 off highway miles on it in the mountains of Montana, it's proven.
I've been getting between 90 to 100 mpg.
Since I bought the bike I've installed front and rear racks, get good ones, they are the best tie down points when hauling.
Got rid of the factory tires and installed 40/60s, the factory tires were 80/20s. Huge off road performance enhancer, I waited too long to do it, the 80/20s were new and I wanted to get some miles out of them before I junked them, I wouldn't wait to do that again.
I went with the Black Widow rack system and I'd buy it again, it's worked out to be perfect for a light weight bike.
If you're considering a bike hauling rack such as this get one with a minimum of a 5ft ramp, the shorter the steeper.
I use the Rino brand 1 1/4 inch wide tie downs.
I tie down at 4 points, a bit overkill but it don't budge when hauling on rough roads. I watch it with my backup camera, it never wiggles.
So, that's my two cents worth, good luck.