My main worry in the boonies is two legged varmints, and then four legged, so a handgun with sufficient power is a must. This rules out the .22's. On the other hand, almost all the shooting will be plinking for fun, much of it by my wife, kids and friends, so something easy to shoot is a must. Not much fills that bill like a .38/.357 revolver.
My own preference is a stainless Smith Mod 60 j-frame with 3" barrel and adj sights. Small enough to pack easily, big enough to shoot easily. Will fire anything from cheap .38 reloads to heavy .357 loads. The titaniums are lighter but pack a nasty kick, plus you can't shoot lead bullets in them.
BW