A very slight one, only. I'm finishing off a can of 3031. And didn't feel like breaking the seal on a can of 335 or TAC.
And I read that the original powder Stoner designed the 5.56 around was a modified 3031.
After loading a box, I can see why they wanted to go with a ball powder so badly!
I think I'll finish off the can by loading 30-30 or 25-35!
Sycamore