I'm most of my way through an 8# keg. Is it the best powder for every application, no. Have better powders been made since, yes. I'm not in a local where temperature sensitivity is an issue
I have primarily used it in the .223 and 5.56. I've also used it in the .243 with 58 gr bullets and in the .308 with 110-125 gr bullets. Accuracy in the .223 has been excellent. Accuracy in the .243 and .308 hasn't been so great when I did load work so I don't use it in those rounds. Muzzle blast from the .243 and .308 have been most impressive.
A pound of H-335 will serve you better than an empty shelf of a better powder.