H4350 or H4831 in 280 rem ?
I don't use either one in the half dozen 280's I've had or still have.
But of the two mentioned, H4831, hands down..........it will work well enough with 140, 150, 160 & 175 grain bullets.
I've found that RL-19 is best all around for me with 140's & for 150's & heavier, RL-22 or Norma MRP (interchangeable) are better performers...........H4831 might be a better choice if only hunting in -20F weather, but that's about the only time; I've not been hunting much in that kind of weather lately, myself.
RL-26 is reputed to be even better, but since I haven't tried it yet myself, I can't directly vouch for it.
MM