I've started every mono I've shot at .050 off the lands. Most are seated to the front of the first band and I've shat in tall cotton.
Yep; that is my experience as well. Never found em the least bit "finicky" just start em way back from lands and VIOLA! Tight little clusters.
I just finished fire forming some 280AI cases w/ my new rifle & have some 140 TSXs loaded up w/ RL22. I don't have the data in front of me, but IIRC my start was 59 & highest I went 63?
I'd suggest having your friend check that .280 AI Nosler brass for fit in his chamber. A lot of guys w/ old .280 Rem Ackley Improved chambers have had issues with it. He might be best off to buy some factory 280 ammo & fireform to his chamber.