I had a 6.0L in my 2003 Yukon XL, which was a 3/4 ton SUV; GMC version of the Suburban. Got it with roughly 100k and sold it with roughly 150k.
Things that I had to fix:
-Pump rub (Google it
)
-Fuel pump
-Alternator
-Throttle body actuator
-Stepper motors in dash
-Lights in dash
-Blower resistor
-Window module in door
I was surprised by the pump rub, as infant mortality seems to be more common. Mine chewed through the case shortly after I bought it. The fuel pump issue doesn't seem that uncommon.
Jason