As much as I want accurate, I also want performance on game. Caribou are relatively easy to kill but I don't want bullets blowing up either.
Barnes is my go-to for most hunting. ELDs at subsonic veolicty out of my 10.5" blackout fragmented badly enough on a CNS neck shot that half a shoulder was lost. I can't imagine what would have happened with something moving even faster.
Interestingly, 125SST out of the same rig (obviously over twice the speed, 2200ish fps) yielded no fragmentation found, complete pass-through, inch-ish sized exit hole and lung soup with a 25-yard "escape" and then drop. Caribou are a bit larger though, so I'd side with you that something more sturdy is in order. for a 6.5, 100/120TTSX or 120/130 TSX BT (there's a 130 FB as well) would not disappoint. Yes there's cheaper options out there for range time and such, but i do love me some Barnes leg-humping time. Guilty pleasure.