I'd recommend that you get what suits your needs right now, and spend less time worrying about possible future uses. If and when you go to the dark continent buying another rifle will seem cheap compared to the cost of everything else. If you are shoe-stringing it remember that a plane ticket and no rifle will get you closer to Africa than a rifle and no plane ticket. You can save enough in ammo cost shooting a 30-06 to pay for the .375.
Now, that's about the best answer to this question I've read and a great summary in general.
DF
