I wouldn't hesitate to put a 185 berger through the lungs out to about 800 with my 308, it shoots so well, and the bergers work really well.
Seeing that I've killed with bigger TSX at 800 that were not going fast either on caribou, I suspect there would be no issue.
The biggest thing is conditions allowing first round dead on placement.
When you take the oil out, the motor locks up sooner or later.
