The 450 Alaskan with 400 gr FP Alaska Bullet Works FP bullets or Hawk heavy jacketed FP bullets in a pre-warModel 71 tends to even the playing field.
Fred Huntington noted years ago that Harold Johnson-who smithed the original 50 Alaskan-said that it worked on
most anything in Alaska-with his 50 BMG bullets truncated forward and handloaded.
I would feel more comfortable with custom bullets in the 50 Alaskan. In Alaska. Pre-war Model 71 Winchesters? Personal experience.