I am about to get my second replacement set at 75k miles and my friend is about to get his third set of replacements at 100k.
Because they put undersize tires on it to increase mileage, but the weight is high for the size of the car because of the battery packs. We rented a 2012 Altima a few year ago to go in to NYC for the day. Ran 75mph all the way out and back, stop and go in the city, then ran up to Watkins Glen for the vintage races on Sunday. 34mpg for the weekend, comfort in spades, loads of room, good handling. And an Altima will run 250k miles without real issues.