I like the .300 Weatherby for this reason. Anywhere Americans hunt will likely have .300 Win or Weatherby ammo somewhere and while I don't recommend it regularly, I would not let shooting .300 Win ammo in a Weatherby chamber ruin a hunt if I was in a bind. Would probably not be great for the throat, but it would work. I also as of late have been loading my Weatherby to WSM ballistics, which makes it much more pleasant.