Hard to figure what your concern is. (I'm assuming these aren't prairie dog, or even antelope loads for sniping at 450 yards.) Perhaps you're concerned about the way the groups moved on the target? That could either be a light issue, or a mechanical problem which changed between the first and second session. I'd probably just adjust left and up and inch in both directions, shoot 3-4 more groups, and call it good. If you can't kill your moose or elk with that combo, the fault isn't with what, but rather how or where.
