Did it on a black bear hunt over hounds this year already. Suppose that don't count though as that is a guarantee for a close up shot. 44 mag pistol with some stiff 240 grain loads. Closed the deal rather nice though breaking the shoulders and taking out the engine room.
I have a Ruger Hawkeye 30-06 with Williams Irons that is my dedicated Bear Rifle. I usually run a 200 gr partition out of it and I have it zeroed at 150 yds. just in case. That gets me to 300 with no issue on bear and is still dead on real close for over the dogs. I do like the NECG peep for my Rugers. They're solid and accurate. I've had them on bolts and single shots. They even held tight on a No.1 45-70 I had that I loaded hard cast loads at "hammer of Thor" levels.
So, yes. I will hunt with Irons this year.......again