Over the last several decades I have tried, trialed, just about every sock and sock combination that's come down the pike. While I use synthetics for everything else, I believe that wool is far and away the best material for socks. Nothing else matches the performance of 2 pairs of wool socks, that fit properly, in whatever boots you're wearing. This holds true in waders as well.
Carrying a second set and changing at mid-day can be an amazing trat to yourself.
Inspect he label of any wool sock you are considereing. The closer the socks are to 100% wool, the better they will perform. It seems that, particularly since merino wool came along, a lot of socks are labeled as wool, but closer inspection of the label will show that wool to be a minor ingredient. Avoid these!
