I've been buying trucks and SUV's since the 1970's. All but one were 4X4. Thought I didn't need it and made the mistake of buying one 4X2 truck, worst car buying decision I ever made. Not a lot of downsides to just staying with a 4X4.
Dodge has a reputation for good drive train reliability. The interiors and other small stuff seems to break down sooner than other trucks, but used are often bargains.
I'd skip the V6 as someone else said. Just not enough difference in fuel mileage and they will be underpowered in a bigger truck.
A lot depends on where you live. Around here Fords outsell Dodge and Chevy by a wide margin. Meaning there are a lot more on used lots at better prices for comparable trucks.
We can argue all day about which is better, Ford, Dodge, Chevy, Toyota, or Nissan. At the end of the day they all have issues and strong points. It comes down to which are most important to you and the one you get the best deal on.
