My current go-to combo is a Kimber Montana, Leupold Vari-X II 2X7, and Federal Fusion .308 165gr factory loads.
Easy to carry, good weather resistance, accurate, flexible enough for shots from arms length out to several hundred yds, and enough bullet weight for big deer.
But its not my only deer rifle! Last count I have 7 lever or bolt actions in the 25 to 35 caliber bracket that I'd consider suitable for deer.
