Your case is much less than full.
Some powders are position sensitive, and some are not. If H110 is position sensitive, you will get distinctly different results if you lower your muzzle into position (powder at the rear of the case) vs. raise it into position (powder at the front of the case).
If you think that's an issue, I have some notes on a few powders that are sensitive/not sensitive that I could look through for you.
