There is no wrong answer here, but every deer season I am reminded of how well the 7mm-08 works on 100-200lb stuff, with cup/cores at moderate speeds and mono-bullets at higher speeds. Then again, I've had some good results as well from the 6.5's, just less experience. My main two deer rifles these days are a lightweight 7mm-08 carbine for toting and a heavy 6.5mm for sitting. So I like them both......
