I have a friend who shot a 9 pt buck at 192 yards, measured, with a 44 mag. The buck turned to run away and he raised and shot. He hit it about 2" from his rear end hole, and we found the bullet in the neck. It traveled completely through the deer under the spine. Deer dropped like a freight train hit it. Friends father said, "I don't know how you made that shot". Friend said he aimed about a foot high at the tip of his tail and shot. He knew the bullet would drop. He was only about 16 or 17 at the time. He said, today he would not take that shot, but he wanted a deer really bad.
So yes, a 44 mag can kill out to 150 yards. Might have to aim high at a distance. If you are using a scope, probably sight in about 3-4" high at 100. It would probably be 3-4" low at 150. They make a big hole.
