DK and SMACARAC3,
I'm with you and the others who favor the 250 Savage as a perfect choice for deer and Pronghorns. I had a short-action Ruger barreled for that cartridge in about 1990 and have never had to "second guess" that choice. With the 100 grain Hornady SP backed by 38.5 grains of H380, it has been a stellar performer on deer, Pronghorns, and a lot of varmints. If there's a more "user-friendly" cartridge for these purposes, I don't know what it would be!
M. Bell