I've used the .22 Magnum out of a handgun enough to know it kills really well - much better than a .22 RF. Anchors big, tough desert jacks w/o a doubt. I've got a buddy who says it works well on called, close range coyotes, fox and bobcat from a rifle.
I've got a .25-20 which hasn't killed anything yet. Sweet shooter and apparently plenty powerful for even deer if carefully hit at short range.
I've used the .22 Hornet as well. I always found the factory HP's to hold together better and do not tear up the edible stuff as bad as the soft points made for that round by the bullet companys. Another very useful rd. that's good to at least 200 yds. E
