I like the 260 Partition with RL 15. I have used this load in 2 of my own 375 and a buddys. All have shot this combo well. You can get 2750 in a 24" barrel w/o leaning on it to hard. We have only used this bullet on black bear, and the bears dont even seem to slow it down, just whistles on through. With the 270 TSX you can get 2750, also with RL 15. I have tried H4350, IMR 4350, IMR4064, H4895, but RL15 is THE powder for the midweights. I have a box of 270 interlocks, but havent loaded them up yet. The 260 accubond might be worth looking at, if you are going to try and squeeze every once of trajectory out of the Ol' Brit
Once you get a load worked up, get off the bench and shoot from field positions. Your shoulder will thank you. Have fun, its great cartridge.
