I'm not sure I'd want to fling a 125 gr. Ballistic tip, Hornady, or Sierra at a deer moving at 3300 fps. I've done it at 3000 and a ribcage shot looks like a varmint bullet hit. As long as you don't have to penetrate more than a few inches you're fine, but I wouldn't try the "thru-shoulder" shot on a deer with one at that velocity. 130 gr. Barnes, sure, why not?
