Joe,
It is interesting that you found IMR4320 to shoot well for you with a 140gr bullet. Was it better than other powders tried?
It gave good accuracy at the highest velocity thus far but, lighter charges don't do as well. My standard load utilizes a caseful of Accurate MR-3100 and a Hornady 139 which is delightfully accurate although slower than most folks desire. My hunting conditions dictate a max range of 125 yards so velocity is not an issue.