I have not had good luck with 350's in mine. I built a m77 left hand SS 458. with a 21' Mcgowen barrel. My twist must not be right. I get the best results with 400-500 grn bullets. Slow them down and they will thump you less. I give you a few of my favs. and you can sort them out. (These are safe in my rifle)

69.7gn H-Varget under a 450 gr hawk RN 1930fps
46.1 gn ACC XMP 5744 405 jacket 45-70 1894fps (adv) good acc load
44.8gn ACC XMP 5744 450 grn hawk 1765fps

Thes are a bit faster but good accurate loads in my M77.

65.2gn IMR 3031 450 hawk or X bullet 2055 accurate
or 57.6 grn of RL 7 and the same bullets about the same speed. This will turn a bull nilgai inside out <img src="/ubbthreads/images/graemlins/smirk.gif" alt="" />