I have some loaded up to test. I have been using 35 grain Vmaxs over 12 grains of Blue Dot and they vaporize red squirrels and chipmunks nicely. The Blue Dot is getting me 3200 give or take a little in a Varmint Special 700 .223. Because the Noslers are 32 grainers they might make a little more. Both the Vmaxs and Varmint Grenades shoot to about an inch in the gun with the BD. I have not seen near the splatter factor out of the VGs that the Vmaxs produce. My guess is that the VGs need a little more speed and a little more resistant target. I got satisfactory results out of a .243 on red squirrels with the VGs