I like the 180 gr NBT for just about everything I normally hunt (deer, paper, water-filled milk jugs) w/ RL-15.
I've gotten good results w/ the 200 gr Int & an over max load of H-380 (in my rifle). IMR-4350, -4320, BLC-(2), RLs -15 and -17 have all done well under the 215 gr Sierra Gameking (a sleeper for this cartridge... high BC, built TOUGH, and ACCURATE!). RL17 & IMR-4350 w/ the 225 gr Int, Big Game and Hunter w/ a 250 gr Barnes O (Big Game a tad more accurate, Hunter a tad faster).
As others have said this is an awesome cartridge. I'd say it rivals its parent for versatility on big game and that is saying something cuz I absolutely LOVE the 'ole Springfield!
