4895, generally the IMR version, is one of my standard powders for the 45-70. It isn't generally the one that'll go absolutely the fastest, but it is a good reliable powder which will lay flat virtually anything you hope to kill with it. It's a fine powder for 350-400 grain cast and jacketed bullets. As a bonus, kind of like H322, you can load it milder or hot and it will shoot well. I've never had an issue with getting it to burn well BTW.