Never have shot TAC, so cant say about that one. Varget, and H-4895 have worked well in both of my 223s in the 50-55 bullet range. Although Benchmark and H-335 are on the top of the powder list for me.
Seafire is definately right about the 223 being like a V.W. as its hard to find a powder that doesnt work.

As far as the 22.250 and those bullets, 38 grs H-380 to start, and work up. H-380 and the 22.250 go together like bread and butter. Perfect.

Good Luck
Swifty



Swifty