A 25-06 loaded with 100gr. TTSX's and a 300WSM loaded with 180gr. TSX's would be my 2-gun choice and loads for NA game. 'Course, I don't prefer to live that way, but if I had to make that choice, those 2 offerings would more than suffice.

Of all the cartridges I've ever hunted with, the 25-06 truly exhibits the 'little big man image' with convincing results.