I've made multiple summer camping, hiking trips in Colorado, Montana, and Wyoming. Only been able to sneak in 1 hunt so far. My house is at 900', but I do most of my hunting at 2000-3000' elevation here in N. Gerorgia so I'm pretty used to climbing up and down hills. My wife and I get in a few hikes in Tennessee each year where we have a chance to get above 6000' which helps. While not the same elevation as the west, the mountains are just as steep here.
I've always been a little run down for the first 48 hours or so after getting above around 6000'. But by the 3rd day I don't notice any difference from being at home. At least so far. As I get older it may take longer next time.
I don't think there is much you can do to completely eliminate issues, but believe the better shape you are in to begin with the faster you will adjust. You are on the right track.
