The 154 grain Hornady you mentioned is an all time favorite of mine. 48-49 grains ( lot difference) of H4350 gives me about 2800 fps in a 22" barrel with RP brass, CCI 200 primer.
Bob Hagel said 52 grains of 4350 (he did not indicate IMR or H) with a 160 grain NPT gave him 2816 fps. WW cases, CCI 200 primers. Temp was 70 degrees. It was safe in a Ruger M77 22" bbl.
